Epithelial to mesenchymal transition, or EMT for short, is a natural process during embryonic development, but has also been shown to play an important role in tumor progression. In collaboration with Þórarinn Guðjónsson at the stem cell research unit at the University of Iceland, Gunnhild Mælandsmo at the Oslo University Hospital and Siver Moestu at NTNU in Tröndheim, we are working towards understanding how metabolism contributes to breast cancer dissemination. Towards this end, we employ in vitro cell models of EMT that we investigate through a combination of cell biology assays including transcriptomics, proteomics and metabolomics. Integrated analysis of these data is performed using tailor made metabolic network models of EMT that we can then interrogate in silico to better account for how biochemical interactions synergetically contribute to EMT. Through this approach we aim to identify biomarkers and novel therapeutic strategies for breast cancer.