Óttar Rolfsson and Bernhard O. Palsson, Decoding the jargon of bottom-up metabolic systems biology, BioEssays, Article first published online: 11 MAR 2015, DOI: 10.1002/bies.201400187
Bottom-up metabolic systems biology is of particular relevance to biochemists. The jargon of bottom-up metabolic systems biology however represents a major obstacle that needs to be overcome. Herein, we diminish this early hurdle by providing a lexicon of the most important terms.
Rohatgi N, Nielsen TN, Bjørn SP, Axelsson I, Paglia G, Voldborg BG, Palsson BO, Rolfsson O, Biochemical Characterization of Human Gluconokinase and the Proposed Metabolic Impact of Gluconic Acid as Determined by Constraint Based Metabolic Network Analysis, PLOS ONE, June 2014 9 (6)
Here we report the recombinant expression, purification and biochemical characterization of isoform I of human gluconokinase ...
Thiele, I., Swainston, N., Fleming, R.M.T., et al. ''A community-driven global reconstruction of human metabolism'', Nat Biotech, doi:10.1038/nbt.2488 (2013).
Here we describe Recon 2, a community-driven, consensus 'metabolic reconstruction', which is the most comprehensive representation of human metabolism that is applicable to computational modeling.
Heinken, A., Sahoo, S., Fleming, R. M. T., Thiele, I., "Systems-level characterization of a host-microbe metabolic symbiosis in the mammalian gut", Gut Microbes, 4(1):1-13 (2013).
In this study, we assembled and validated a genome-scale metabolic reconstruction of Bacteroides thetaiotaomicron (iAH991)...